The National Times - Stock markets drop amid tech concerns before rate calls

Stock markets drop amid tech concerns before rate calls


Stock markets drop amid tech concerns before rate calls
Stock markets drop amid tech concerns before rate calls / Photo: © AFP

Major European and Asian stock markets mostly fell Thursday after more losses on Wall Street's Nasdaq, where technology firms are under pressure over concerns about vast AI investments.

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The Bank of England (BoE) was widely expected to keep its main interest rate on hold Thursday, shortly ahead of a likely similar decision from the European Central Bank (ECB).

The British pound slid as Prime Minister Keir Starmer fights for his political life amid a storm of protest for appointing Peter Mandelson as ambassador to the United States, despite knowing about his close ties to convicted sex offender Jeffrey Epstein.

The yield on 10-year UK government bonds jumped to 4.59 percent, the highest level since November.

With no rate changes expected from either the BoE or ECB, traders will be looking for any changes to their outlooks on growth and inflation.

The central bank updates are "set to provide further catalysts into an already volatile and unpredictable market that has seen sharp tech and precious metal declines over the past week", said Joshua Mahony, chief market analyst at Scope Markets.

Investor caution also remains high after Anthropic, which created the AI chatbot Claude, unveiled a tool that could be used by firms to carry out legal work.

Its announcement Tuesday hit firms across the software, financial services and asset management industries, though analysts said there has been a general shift by investors out of tech following years of eye-watering gains.

An underwhelming response to earnings from titans including Alphabet, ARM and Microsoft has further fuelled that move, which also comes as questions are raised about the wisdom of pumping hundreds of billions into AI with little idea about the timing of returns.

Fiona Cincotta, an analyst at City Index, said that "while losses in tech continue, sentiment remains fragile".

Silver prices tanked almost 11 percent Thursday as a sell-off in precious metals resumed after a brief spell of calm following massive selling when records were reached last week.

Gold, traditionally seen as a safe-haven, lost 1.8 percent.

Oil prices dropped after Iran and the United States said nuclear talks would go ahead in Oman this week.

The news soothed investor concerns sparked by a report Wednesday that the bitter foes would not meet owing to a row about the format and the venue, which sent the price of both main contracts up more than three percent.

Bitcoin briefly fell to $70,010 as investors reconsidered their holdings of riskier assets, with the cryptocurrency now down more than 40 percent from its record high above $126,000 in October.

In corporate news, shares in Panasonic closed up 8.4 percent in Tokyo after the Japanese electronics giant said that alongside rising profit that it would increase its job cuts to 12,000 as part of a restructuring drive.

Sony closed slightly higher after hiking its full-year sales and profit forecasts thanks to a weaker yen.

In London, oil giant Shell was down one percent in midday deals on a mixed earnings update.

- Key figures at around 1100 GMT -

London - FTSE 100: DOWN 0.3 percent at 10,375.47 points

Paris - CAC 40: UP 0.3 percent at 8,282.31

Frankfurt - DAX: DOWN 0.2 percent at 24,552.56

Tokyo - Nikkei 225: DOWN 0.9 percent at 53,818.04 (close)

Hong Kong - Hang Seng Index: UP 0.1 percent at 26,885.24 (close)

Shanghai - Composite: DOWN 0.6 percent at 4,075.92 (close)

New York - Dow: UP 0.5 percent at 49,501.30 (close)

Euro/dollar: DOWN at $1.1793 from $1.1802 on Wednesday

Pound/dollar: DOWN at $1.3595 from $1.3648

Dollar/yen: UP at 157.17 yen from 156.92 yen

Euro/pound: UP at 86.77 pence from 86.47 pence

Brent North Sea Crude: DOWN 1.3 percent at $68.54 per barrel

West Texas Intermediate: DOWN 1.3 percent at $64.27 per barrel

H.Davies--TNT

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A material that turns your own movement into medicine has just landed a corporate home. PetVivo Holdings (OTCQX: PETV), a veterinary biotech and biomedical device company focused on treating osteoarthritis in dogs and horses, has acquired PiezoBioMembrane (PBM) — a startup built around a biodegradable implant that generates electricity from the everyday force of a joint in motion, and uses that charge to help regrow cartilage from the inside out. The material is the invention of Thanh Nguyen, a professor of mechanical engineering in UConn's College of Engineering, who founded PBM in 2021 to advance new implementation methods for his work with piezoelectric materials — substances that convert mechanical force into electrical energy. These materials are typically ceramics: hard, brittle, and poorly suited for medical use. But Nguyen's lab developed new forms that are so , flexible, and biodegradable, breaking down naturally within the body over time. wound healing, The materials have already shown strong potential across a range of medical applications, including tissue regeneration, implanted force sensors, and targeted drug delivery in tumor treatment. How It Works biodegradable ultrasound for In the case of arthritis, Nguyen explains, the piezoelectric materials function as an off-the-shelf product that can be implanted or injected directly into the ailing joint — with no drugs, chemicals, or cells required. The everyday force exerted on the joint generates a small electrical charge, which helps regrow healthy cartilage, mimicking the body's natural use of electricity to regenerate tissue. "The body can be electrically stimulated to regrow," Nguyen says. PBM's materials "act like a battery — an everlasting battery that works whenever there is a force applied, and vanishes safely inside the body over time." PetVivo's Vision for the Acquisition PetVivo Holdings CEO John Lai expressed enthusiasm for the merger's potential to improve the lives of companion animals globally. "PBM has developed a compelling functional biomaterials platform with the potential to support the development of multiple medical device and therapeutic product lines across both human and animal health markets," Lai said in a press release. "By combining PBM's scientific innovation with PetVivo's product development capabilities, commercialization experience, regulatory expertise, and public company infrastructure, we believe we can accelerate theadvancement of technologies that may serve as the foundation for numerous future products and strategic opportunities." For Nguyen, the deal is a chance to scale technology that could eventually benefit both animals and people. "PetVivo is an animal health company, but they do have a big passion: pushing the technology towards clinical trials for human use," Nguyen says. "That aligned perfectly with my passion for developing technology that has an impact on human life. That is why I am excited about this merger, which facilitates my passion." A Track Record of Innovation Nguyen's research sits at the intersection of medicine, micro/nanotechnology, and biomaterials. His inventions have earned him publications in prominent scientific journals and media coverage from outlets including NPR. Nguyen founded PBM during the COVID-19 pandemic, a er realizing the material he had developed could be used to create an especially effective, biodegradable face mask — one where the mechanical force of breathing generated an electrical charge that provided an extra layer of protection against viruses. PBM is not Nguyen's only venture in the acquisition pipeline. His other startup, Single-Time Microneedles (STM), is also currently undergoing an acquisition process. STM has pioneered stable, efficient vaccine delivery technology in the form of an adhesive patch. shelfNguyen's focus on biodegradable materials has translated into a remarkably diverse range of medical applications. He has received five R01 grants from the National Institutes of Health (NIH) supporting research in cartilage regeneration, bone regeneration, HIV antibody delivery systems, and biodegradable ultrasound technology to boost the effectiveness of chemotherapy for brain cancer. "Whatever we are working on, we want to show that it works very well in vitro and in vivo," Nguyen says. "Then, when we are at the point of commercialization, we set up a startup or license the technology — or maybe team up with an industry partner." Thanh Nguyen is a professor of mechanical engineering in UConn's College of Engineering. (Courtesy of Thanh Nguyen

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